Figure 1

Results of RT-PCR after treatment with FG 7142 in the hippocampus of (A) adult and (B) neonatal mice. FG 7142 (10 or 20 mg/kg) or the vehicle was intraperitoneally injected into the adult (postnatal days 56) and neonatal (postnatal days 8) mice. The mice were sacrificed at one hour after the administration. (A) The data of adult mice are presented as a percentage of the mean value of the vehicle-treated mice and are mean ± SEM obtained from 6 or 7 animals. The statistical analysis was carried out by one-way ANOVA followed by the post hoc Dunnett’s test. * p < 0.05 compared to the vehicle-treated controls. (B) The data of neonatal mice are presented as a percentage of the mean value of the vehicle-treated mice and are mean ± SEM obtained from 9 or 10 animals.