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Table 2 Reaction to novelty in VEH and DAT-i mice, in a novelty-seeking test

From: Immunization with DAT fragments is associated with long-term striatal impairment, hyperactivity and reduced cognitive flexibility in mice

Parameter Activity rate Time (%) in novel Crossing/min
VEH controls 3.79 ± 0.21 79.7 ± 1.09 2.55 ± 0.26
DAT-i mice 4.10 ± 0.22 78.6 ± 1.75 2.98 ± 0.33
  1. After a three-day familiarization to one side, mice had free-choice access to a novel side of the apparatus. Mean (±SEM, n = 12 per group) activity rate (number of beam interruptions per second), time (%) spent in the novel side, and frequency of crossing to the familiar side, measured via photo-beam interruptions by mice on the testing day.