Association of estrogen receptor alpha gene polymorphism with age at onset, general psychopathology symptoms, and therapeutic effect of schizophrenia

Table 1 Association analysis of SNPs with schizophrenia

dbSNP ID	Group	Cases						Controls						p-value
dbSNP ID	Group	N	HWE ( p)	Genotype			MAF	N	HWE ( p)	Genotype			MAF	Genotype	Allele
rs2234693				TT	TC	CC				TT	TC	CC
	All	303	0.55	109	150	44	0.15	292	0.71	111	141	40	0.14	0.868	0.612
	Male	152	0.86	63	71	18	0.12	146	0.46	60	71	15	0.10	0.894	0.876
	Female	151	0.51	46	79	26	0.17	146	1.00	51	70	25	0.17	0.692	0.574
rs9340799				AA	AG	GG				AA	AG	GG
	All	303	1.00	194	97	12	0.04	292	0.85	189	93	10	0.03	0.938	0.789
	Male	152	0.50	91	51	10	0.07	146	0.53	104	40	2	0.01	0.025	0.010
	Female	151	0.37	103	46	2	0.01	146	1.00	85	53	8	0.05	0.057	0.031

Boldface letters represent that the Bonferroni corrected p-values are still less than 0.05.

ISSN: 1744-9081