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Table 2 Genotype and allele frequencies of G2385R, P268S, and IVS9 in cases and controls

From: P268S in NOD2 associates with susceptibility to Parkinson’s disease in Chinese population

Genotype PD patients, n = 237 Control, n = 190 Odds ratio (95% CI)* p value** Power§
  No. % No. %    
G2385R(G > A)        
GG 213 89.9 186 97.9 1  
GA 24 10.1 4 2.1 5.24 0.009 0.8973
(1.79-15.38)
AA 0 0 0 0  
G 450 94.9 376 98.9 1  
A 24 5.1 4 1.1 5.01 0.090 0.8803
(1.72-14.58)
P268S(C > T)        
CC 229 96.6 190 100 1  
CT 8 3.4 0 0 0.045 NA
TT 0 0 0 0  
C 466 98.3 380 100 1   
T 8 1.7 0 0
IVS9(G > A)        
GG 207 87.3 175 92.1 1  
GA 30 12.7 15 7.9 1.7 0.348 0.2987
(0.88-3.24)
AA 0 0 0 0  
G 444   365 96.1 1  
A 30 6.3 15 3.9 1.64 0.572 0.2865
      (0.87-3.10)   
  1. *: Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated by comparison to the common allele frequencies and genotype frequencies.
  2. **: Fisher exact test and false discovery rate were used to calculate and correct the p values, respectively. Two sided P value ≤ 0.05 was considered statistically significant.
  3. §: Power was calculated by Power and Sample Size Calculations Version 3.0, 2009. NA: not available.