Figure 6From: Slow angled-descent forepaw grasping (SLAG): an innate behavioral task for identification of individual experimental mice possessing functional visionSLAG identifies individual mice possessing functional vision, as validated by DC preference test. Data are pooled together from an age-ranged cohort of 158 B6 mice (57 wild-type, 101 knockout, age range 44–241 days; separate data for individual mice from each genotype appear in Figure 7). (A) Visualization of SLAG and DC performance as a function of age. No evidence for correlation between age and DC preference was observed: SLAG(−) R2 = 0.0012, SLAG(+) R2 = 0.0135 (regression lines not shown). (B) Mean time spent in DC: SLAG(−) = 50%, SLAG(+) = 69% (unpaired two-tailed t-test, means are significantly different, p < 0.0001; two-tailed Mann–Whitney test, p < 0.0001; mean +/− SE bars displayed). Note that every SLAG(+) mouse spent >50% time in DC. (C) Histogram visualization of the data in (B) shows that the SLAG(−) population appears roughly symmetrical, passing the Kolmogorov-Smirnov (KS) test for normality (α = 0.05). (D) Histogram visualization of the data in (B) shows that the SLAG(+) population follows an asymmetrical distribution with respect to DC preference, failing the KS test for normality (α = 0.05).Back to article page