Behavioral and Brain Functions

Table 1 Pearson correlation of diabetes biomarkers with cognitive impairment biomarkers in diabetic rats

From: Alteration in amyloid β42, phosphorylated tau protein, interleukin 6, and acetylcholine during diabetes-accelerated memory dysfunction in diabetic rats: correlation of amyloid β42 with changes in glucose metabolism

	FPG					Insulin					IRI
	Day 0	Day 15	Day 30	Day 45	Day 75	Day 0	Day 15	Day 30	Day 45	Day 75	Day 0	Day 15	Day 30	Day 45	Day 75
CSF Aβ42	−0.238^NS	−0.865*	−0.548^NS	−0.343^NS	−0.720^NS	−0.267^NS	0.256^NS	0.074^NS	−0.760*	−0.372^NS	−0.388^NS	0.064^NS	−0.443^NS	−0.946*	−0.625^NS
Blood Aβ42	0.257^NS	0.744^NS	0.497^NS	−0.767^NS	−0.002^NS	−0.742^NS	0.669^NS	−0.790^NS	−0.036^NS	−0.411^NS	−0.481^NS	0.365^NS	−0.151^NS	−0.869^NS	−0.130^NS
ACh	0.128^NS	0.137^NS	0.101^NS	−0.079^NS	−0.347^NS	0.028^NS	−0.032^NS	−0.490^NS	−0.009^NS	−0.608^NS	0.338^NS	0.256^NS	−0.310^NS	0.888^NS	−0.874^NS

The Pearson correlation test was used for evaluation of relationships between the various biomarkers (n = 25). P < 0.05 (*) was adopted as the significance level for all tests. P > 0.05 (^NS) was not considered significant.
CSF Aβ42 amyloid β42 in cerebrospinal fluid, Blood Aβ42 Aβ42 in blood, IRI insulin resistance index.

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ISSN: 1744-9081

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