Table 2 Analysis of the association studies between the DRD2 gene TaqI polymorphism and SZ in all populations and in a Caucasian sub-group
Model analysis | Model effects | p value of Q test | ||
|---|---|---|---|---|
Random OR (95% CI) | Fixed OR (95% CI) | |||
All populations | ||||
 Allelic | With heterogeneity | 0.92 (0.71–1.19) | 0.89 (0.80–0.99) | <0.00 |
Without heterogeneity | 0.92 (0.79–1.07) | 0.92 (0.81–1.05) | 0.256 | |
 Additive | With heterogeneity | 0.59 (0.30–1.14) | 0.51 (0.37–0.71) | <0.00 |
Without heterogeneity | 0.57 (0.38–0.86) | 0.57 (0.39–0.81) | 0.326 | |
 Recessive | With heterogeneity | 1.34 (0.88–2.05) | 1.17 (0.95–1.44) | <0.00 |
Without heterogeneity | 1.50 (1.10–2.03) | 1.50 (1.10–2.03) | 0.664 | |
 Dominant | With heterogeneity | 0.72 (0.49–1.06) | 0.72 (0.62–0.84) | <0.00 |
Without heterogeneity | 0.85 (0.72–1.01) | 0.85 (0.72–1.01) | 0.586 | |
Caucasian population | ||||
 Allelic | With heterogeneity | 0.88 (0.66–1.18) | 0.86 (0.77–0.96) | <0.00 |
Without heterogeneity | 0.86 (0.71–1.05) | 0.86 (0.71–1.05) | 0.551 | |
 Additive | With heterogeneity |  |  |  |
Without heterogeneity | 0.60 (0.36–0.99) | 0.59 (0.39–0.91) | 0.263 | |
 Recessive | With heterogeneity |  |  |  |
Without heterogeneity | 0.90 (0.69–1.18) | 0.90 (0.71–1.15) | 0.403 | |
 Dominant | With heterogeneity | 0.76 (0.50–1.14) | 0.77 (0.64–0.93) | <0.00 |
Without heterogeneity | 0.89 (0.71–1.11) | 0.89 (0.72–1.10) | 0.397 | |