Fig. 3
From: Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
Effects of aging on AMPK/mTOR pathway-mediated autophagy in APP/PS1 mice. A The bands of AMPK, p-AMPK, mTOR, p-mTOR and β-actin (Western blot); B The relative expression of p-AMPK/AMPK over WT-9 M; C The relative expression of p-mTOR/mTOR over WT-9 M. D The bands of Beclin1, LC3, P62 and β-actin (Western blot); E The relative expression of Beclin1 over WT-9 M; F The relative expression of LC3II/LC3I over WT-9 M; G The relative expression of P62 over WT-9 M. Results are expressed as mean ± SD. n = 4, *P < 0.05, **P < 0.01 vs WT-9 M group