Fig. 1

Proposed mechanism for parosmia. Comparison between normal smell processing pathway and distorted perception in parosmia. Smelling an orange would trigger a cascade of reactions via OSNs and travelling all the way to OBs which in turn would project orange smell in the brain. However, in parosmia, due to loss of OSNs and mis-wiring, distorted perception of orange as smoke in the brain. OB, olfactory bulb, OSNs, olfactory sensory neurons