Fig. 2

Open field test. A Illustration of the open field test. B The distance moved was significantly reduced after early precipitated withdrawal (PW) from nicotine (asterisks). C The time spent immobile was significantly increased after PW from nicotine (asterisk). D The time spent in the center zone was significantly reduced after PW from nicotine (asterisks). Data represent the mean ± S.E.M. from 10–11 mice/group