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Fig. 3 | Behavioral and Brain Functions

Fig. 3

From: Behavioral characterization of early nicotine withdrawal in the mouse: a potential model of acute dependence

Fig. 3

Elevated plus maze test. A Illustration of the elevated plus maze test. B The time spent in the closed arm was significantly reduced after mecamylamine injection (MEC) or early precipitated withdrawal (PW) from nicotine (asterisks). C The number of entries into the open arm was significantly reduced after PW, and the number of entries into the closed arm was significantly reduced after MEC and PW (asterisks). Data represent the mean ± S.E.M. from 7–12 mice/group

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