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Fig. 3 | Behavioral and Brain Functions

Fig. 3

From: The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old rats

Fig. 3

The circadian rhythm of horizontal activity detected in actimeter for 24 h (counts) effect of pinealectomy induced in the sham- and pin-operated rats aged 3- A, 14- B and 18 months C. Data are presented as mean ± SEM, n = 8. Two-way repeated ANOVA demonstrated a main time effect for 3-, 14-, and 18 month-old rats (p < 0.001). Post hoc test showed diurnal variability in motor activity in 3-month-old sham rats (zeigeber (ZT)10 vs. ZT14,ZT21 (p < 0.05) (A), in 14-month-old sham rats (ZT0 vs. ZT 12,13,14,1516,17; ZT1 vs. ZT12,13,16,20,21; ZT3 vs. ZT13; ZT4 vs. ZT13,20; ZT5 vs. ZT12,13,16,19,20; ZT6 vs. ZT12,13,14,15,16,18,19,20,21; ZT7 vs. ZT12,13,20; ZT8 vs. ZT12,13,16,20,21; ZT9 vs. ZT13,20; ZT10 vs. ZT13; ZT23 vs. ZT12,13,14,16,18,20 – p < 0.05), in 14 month-old pin rats (ZT5 vs. ZT19—p < 0.05), and in 18-month-old sham rats (ZT0-ZT4 vs. ZT11; ZT5 vs. ZT11,13; ZT8 vs. ZT13; ZT23 vs. ZT11,13,21–p < 0.05). On the right to the figures are inserted Cosinor data

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Behavioral and Brain Functions

ISSN: 1744-9081

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