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Fig. 8 | Behavioral and Brain Functions

Fig. 8

From: The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old rats

Fig. 8

The effect of pinealectomy on the expression of the heat shock protein (Hsp) 70 A and Hsp90 B in the frontal cortex (FC) A, B and the hippocampus C, D of 3-, 14- and 18 month-old rats. Kruskal–Wallis analysis showed a main Age effect [F2,44 = 8.988, p < 0.001] and Surgery x Age [F2,44 = 4.862, p = 0.013] for the Hsp 70. A main Age effect [F2,40 = 13.552, p < 0.001] was also detected for the Hsp 90 in the FC. Data are presented as mean ± SEM. *p = 0.033, 18-month-old sham compared to 3 month-old sham rats; **p = 0.01, 18 month-old sham compared to 14 month-old sham rats; *p = 0.019, 14 month-old pin rats compared to the matched sham rats A. *p = 0.05, 18 month-old sham compared to 3 month-old sham rats; *p = 0.039, 18 month-old sham compared to 14 month-old sham rats B

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Behavioral and Brain Functions

ISSN: 1744-9081

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