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Figure 2 | Behavioral and Brain Functions

Figure 2

From: Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD)

Figure 2

The confirmed changes in the prefrontal cortical and striatal gene expression in cohort 2 spontaneously hypertensive rats (SHRs). qRT-PCR validated the expression of Homer1, S100a9 and Angptl4, differentially expressed genes (DEGs) in the prefrontal cortex (PFC), as well as Pcdh10, Ctnnd1, Uqcrc2, Nedd4, and Perp, DEGs in the striatum of cohort 2 SHRs. The data represent the expression ratios with respect to the control group (Con), and the values were normalized to GAPDH. *P < 0.05, **P < 0.01 significantly different from the control groups.

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