Table 1 The percent decrease in amplitude from baseline of P2 and N2 components in the various brain areas of adult male WKY rats following a single injection of 0.6, 2.5, and 10.0 mg/kg MPD (i.p.).
Component | Brain Area | 0.6 mg/kg MPD | 2.5 mg/kg MPD | 10.0 mg/kg MPD |
|---|---|---|---|---|
P2 | VTA | 15.3 ± 5.5% | 38.8 ± 6.2% | 41.3 ± 10.6% |
|  | NAc | 12.5 ± 9.2% | 20.5 ± 2.7% | 51 ± 5.9% |
|  | PFC | -11 ± 2.2% | 34.3 ± 4.7% | 43 ± 8.7% |
N2 | VTA | 21.8 ± 5.9 | 34.8 ± 6.7% | 55 ± 6 % |
|  | NAc | 23.5 ± 5.9% | 53.5 ± 3.2% | 60 ± 2.4% |
|  | PFC | 29.5 ± 7.4 | 65 ± 6 | 76.5 ± 2.7 |