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Table 3 Serotonin transporter ( SLC6A4 ) single nucleotide polymorphisms (SNPs) investigated in patients with schizophrenia and control subjects

From: Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia

SNP

Base

MAF

Genotype counts (schizophrenia/control)

Allele association

Genotype association

   

Allele 1

 

Allele 2

 

OR

  

OR

OR

 

(1/2)

 

Homozyogotes

Heterozygotes

Homozygotes

p-value

2 vs 1

p-value

 

12 vs 11

22 vs 11

Rs1042173

A/C

0.46

223/410

402/770

207/291

0.083

 

1.11

0.022

 

0.93

1.27

Rs4583306

A/G

0.42

276/475

410/755

173/237

0.020

 

1.16

0.020

 

1.04

1.40

Rs140700

C/T

0.09

689/1233

140/221

2/10

0.435

 

1.09

0.171

 

1.17

0.39

Rs2020942

C/T

0.14

313/528

390/714

128/228

0.359

 

0.94

0.518

 

0.90

0.91

Rs12150214

G/C

0.18

595/982

219/438

21/46

0.123

 

0.88

0.282

 

0.86

0.83

Rs4251417

C/T

0.09

673/1204

148/257

9/7

0.214

 

1.14

0.123

 

1.07

2.78

Rs16965628

G/C

0.06

753/1310

77/152

1/9

0.192

 

0.83

0.125

 

0.91

0.19

  1. The table shows nominal allele and genotype association results with gender and country as covariates.
  2. Nominal allele and genotype association results are reported with gender and country as covariates. MAF, minor allele frequencies in control individuals (allele 2 in the table).
  3. Nominally significant; after correction for multiple testing using permutation test, all P- values > 0.10.
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Behavioral and Brain Functions

ISSN: 1744-9081

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