From: Paradox of schizophrenia genetics: is a paradigm shift occurring?
Genes and SNPs | Location | Allele (min/maj) | m A | m U | OR | d |
---|---|---|---|---|---|---|
IL1B | 2q13 | Â | Â | Â | Â | Â |
rs16944 | Â | T/C* | 0.6289 (N=1,718) | 0.6066 (N=2,157) | 1.11 | 0.022 |
ZNF804A | 2q32.1 | Â | Â | Â | Â | Â |
rs1344706 | Â | G/T* | 0.6357 (N=6,487) | 0.6032 (N=11,478) | 1.14 | 0.033 |
CCKAR | 4p15.2 | Â | Â | Â | Â | Â |
rs1800857 | Â | C*/T | 0.1666 (N=105) | 0.1559 (N=93) | 1.32 | 0.008 |
GABARB2 | 5q34 | Â | Â | Â | Â | Â |
rs1816072 | Â | C/T* | 0.6404 (N=1,129) | 0.5935 (N=995) | 1.22 | 0.047 |
rs194072 | Â | C/T* | 0.8685 (N=1,137) | 0.8466 (N=991) | 1.20 | 0.022 |
rs6556547 | Â | T/G* | 0.9444 (N=774) | 0.9226 (N=620) | 1.43 | 0.022 |
DTNBP1 | 6p23 | Â | Â | Â | Â | Â |
rs3213207 | Â | G/A* | 0.8891 (N=8,377) | 0.8758 (N=8,886) | 1.11 | 0.013 |
rs1474605 | Â | G/A* | 0.8000 (N=3,710) | 0.7858 (N=3,588) | 1.09 | 0.014 |
HIST1H2BJ | 6p22.1 | Â | Â | Â | Â | Â |
rs6913660 | Â | A/C* | 0.8927 (N=10,065) | 0.8801 (N=34,098) | 1.15 | 0.013 |
PRSS16 | 6p22.1 | Â | Â | Â | Â | Â |
rs6932590 | Â | C/T* | 0.7943 (N=7,177) | 0.8058 (N=28,270) | 1.16 | -0.012 |
rs13219354 | Â | C/T* | 0.9088 (N=6,478) | 0.9020 (N=27,224) | 1.20 | 0.007 |
PGBD1 | 6p22.1 | Â | Â | Â | Â | Â |
rs13211507 | Â | C/T* | 0.9518 (N=9,774) | 0.9387 (N= 33,694) | 1.23 | 0.013 |
RPP21 | 6p21.33 | Â | Â | Â | Â | Â |
rs3130375 | Â | A/C* | 0.9018 (N=2,799) | 0.8634 (N=3,082) | 1.41 | 0.038 |
NOTCH4 | 6p21.32 | Â | Â | Â | Â | Â |
rs3131296 | Â | A/G* | 0.8912 (N=7,156) | 0.8892 (N=28,312) | 1.20 | 0.002 |
rs2071287 | Â | A/G* | 0.6858 (N=2,511) | 0.6463 (N=2,556) | 1.19 | 0.039 |
MDGA1 | 6p21.2 | Â | Â | Â | Â | Â |
rs11759115 | Â | C/T* | 0.8639 (N=1,874) | 0.8379 (N=2,582) | 1.23 | 0.026 |
rs12191311 | Â | T*/C | 0.3619 (N=1,879) | 0.3555 (N=2,605) | 1.12 | 0.006 |
rs7769372 | Â | T*/C | 0.2328 (N=1,915) | 0.1885 (N=2,576) | 1.18 | 0.044 |
AH1 | 6q23.3 | Â | Â | Â | Â | Â |
rs2064430 | Â | T*/C | 0.5672 (N=2,796) | 0.5296 (N=13,494) | 1.13 | 0.038 |
rs11154801 | Â | A/C* | 0.6633 (N=3,298) | 0.6576 (N=14,805) | 1.09 | 0.006 |
C6orf217 | 6q23.3 | Â | Â | Â | Â | Â |
rs10223338 | Â | T/C* | 0.7158 (N=2,797) | 0.6975 (N=13,522) | 1.12 | 0.018 |
rs1475069 | Â | C*/A | 0.7205 (N=3,276) | 0.6976 (N=14,639) | 1.14 | 0.023 |
rs9321521 | Â | A/G* | 0.6755 (N=2,784) | 0.6642 (N=13,311) | 1.12 | 0.011 |
RELN | 7q22.2 | Â | Â | Â | Â | Â |
rs7341475 | Â | A/G* | 0.8327 (N=3,315) | 0.8110 (N=8,042) | 1.14 | 0.022 |
rs262355 | Â | A*/T | 0.3852 (N=1,128) | 0.3563 (N=1,848) | 1.14 | 0.029 |
PPP3CC | 8p21.3 | Â | Â | Â | Â | Â |
rs2461491 | Â | A*/G | 0.4469 (N=6,287) | 0.4353 (N=6,200) | 1.07 | 0.015 |
rs10108011 | Â | G*/A | 0.3657 (N=4,304) | 0.3488 (N=4,465) | 1.09 | 0.0170 |
SLC18A1 | 8p21.3 | Â | Â | Â | Â | Â |
rs2270641 | Â | C*/A | 0.3182 (N=759) | 0.2802 (N=885) | 1.63 | 0.038 |
NRG1 | 8p12 | Â | Â | Â | Â | Â |
rs10503929 | Â | C/T* | 0.8342 (N=3,256) | 0.8118 (N=4,181) | 1.14 | 0.022 |
GWA_10q26.13 | 10q26.11 | Â | Â | Â | Â | Â |
rs17101921 | Â | A*/G | 0.06667 (N=7,447) | 0.04318 (N=13,039) | 1.28 | 0.023 |
DRD4 | 11p15.5 | Â | Â | Â | Â | Â |
rs4646984 | Â | S/L* | 0.7750 (N=1,558) | 0.7292 (N=1,499) | 1.27 | 0.046 |
rs1800955 | Â | C*/T | 0.4235 (N=2,450) | 0.4018 (N=2,506) | 1.12 | 0.022 |
TPH1 | 11p15.1 | Â | Â | Â | Â | Â |
rs1800532 | Â | A*/C | 0.4752 (N=2,416) | 0.4299 (N=3,623) | 1.16 | 0.045 |
rs1799913 | Â | A*/C | 0.4546 (N=1,323) | 0.4171 (N=2,201) | 1.14 | 0.038 |
GWA_11p14.1 | 11p14.1 | Â | Â | Â | Â | Â |
rs1602565 | Â | C*/T | 0.1346 (N=5,475) | 0.1152 (N=10,845) | 1.19 | 0.019 |
DRD 2 | 11q23.1 | Â | Â | Â | Â | Â |
rs6277 | Â | C*/T | 0.4968 (N=3,156) | 0.4527 (N=3,960) | 1.40 | 0.044 |
rs6275 | Â | T*/C | 0.3106 (N=2,436) | 0.2927 (N=2,918) | 1.15 | 0.018 |
rs1801028 | Â | G*/C | 0.0245 (N=4,304) | 0.0207 (N=5,920) | 1.33 | 0.004 |
NRGN | 11q24.2 | Â | Â | Â | Â | Â |
rs12807809 | Â | C/T* | 0.8403 (N=7,213) | 0.8190 (N=28,490) | 1.15 | 0.021 |
OPCML | 11q25 | Â | Â | Â | Â | Â |
rs3016384 | Â | T/C* | 0.5374 (N=5,491) | 0.5141 (N=10,900) | 1.10 | 0.023 |
GRIN2B | 12p13.1 | Â | Â | Â | Â | Â |
rs1019385 | Â | T/G* | 0.5604 (N=687) | 0.4885 (N=650) | 1.33 | 0.072 |
DAO | 12q24.11 | Â | Â | Â | Â | Â |
rs4623951 | Â | C/T* | 0.7038 (N=1,509) | 0.6788 (N=1,521) | 1.14 | 0.025 |
HTR2A | 13p14.13 | Â | Â | Â | Â | Â |
rs6311 | Â | A*/G | 0.4441 (N=2,594) | 0.4115 (N=2,869) | 1.21 | 0.033 |
DAOA | 13q33.3 | Â | Â | Â | Â | Â |
rs778293 | Â | G*/A | 0.3149 (N=2,899) | 0.2770 (N=3,218) | 1.18 | 0.038 |
rs3916971 | Â | T/C* | 0.5622 (N=844) | 0.5211 (N=922) | 1.19 | 0.041 |
AKT1 | 14q32.33 | Â | Â | Â | Â | Â |
rs3803300 | Â | A*/G | 0.1068 (N=1,301) | 0.1039 (N=1,424) | 1.36 | 0.003 |
GWA_16p13.12 | 16p13.12 | Â | Â | Â | Â | Â |
rs7192086 | Â | T*/A | 0.2701 (N=7,179) | 0.2456 (N=12,623) | 1.12 | 0.025 |
RPGRIP1L | 16q12.2 | Â | Â | Â | Â | Â |
rs9922369 | Â | A*/G | 0.0403 (N=6,494) | 0.0336 (N=11,449) | 1.32 | 0.007 |
HP | 16q22.3 | Â | Â | Â | Â | Â |
Hp_1/2 | Â | 1/2* | 0.6208 (N=1,300) | 0.5911 (N=1,976) | 1.14 | 0.030 |
SRR | 17p13.3 | Â | Â | Â | Â | Â |
rs408067 | Â | G*/A | 0.3166 (N=1,145) | 0.2779 (N=1,146) | 1.22 | 0.039 |
TCF4 | 18q21.2 | Â | Â | Â | Â | Â |
rs9960767 | Â | C*/A | 0.0514 (N=9,755) | 0.0467 (N=33,648) | 1.23 | 0.005 |
APOE | 19q13.32 | Â | Â | Â | Â | Â |
e4-allele | Â | E2/3/4* | 0.1391 (N=1,596) | 0.1139 (N=3,038) | 1.16 | 0.025 |
COMT | 22q11.21 | Â | Â | Â | Â | Â |
rs737865 | Â | C/T* | 0.6916 (N=7,397) | 0.6803 (N=10,411) | 1.06 | 0.011 |
rs4818 | Â | G*/C | 0.3503 (N=177) | 0.3081 (N=99) | 1.05 | 0.042 |