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Fig. 3 | Behavioral and Brain Functions

Fig. 3

From: Venlafaxine ameliorates the depression-like behaviors and hippocampal S100B expression in a rat depression model

Fig. 3

Behaviors of the open-field test at different time. The values are expressed as mean ± SD (n = 10/group). Compared with control group “*p < 0.05, **p < 0.01”. Compared with 0 mg venlafaxine group “# p < 0.05, ## p < 0.01”. Compared with 10 mg venlafaxine group “& p < 0.05, && p < 0.01”. a Distance of horizontal motion; b rearing times. On day 22, there were significant differences among the control group and three treated groups in distance of horizontal motion, and rearing times (all p < 0.01). On day 29, there was still significant difference between the 0 mg venlafaxine and control group (p < 0.01). On day 36, there was still significant difference between the 0 mg venlafaxine and 10 mg venlafaxine group (p < 0.01). On day 43, the distance of horizontal motion and number of vertical motion was higher in the 10 mg venlafaxine compared with the 5 mg venlafaxine group (p < 0.01)

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