Neurobiology of brain disorders

  2. Research

    A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs

    Attention deficit hyperactivity disorder (ADHD) is a prevalent and multifactorial neuropsychiatric disorder in the human population worldwide. Complex etiology and clinical heterogeneity have challenged the re...

    Jenni Puurunen, Sini Sulkama, Katriina Tiira, Cesar Araujo, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Behavioral and Brain Functions 2016 12:27

    Published on: 29 September 2016

  4. Research

    Relationship among methadone dose, polymorphisms of dopamine D2 receptor and tri-dimensional personality questionnaire in heroin-addicted patients

    We investigated whether variation in the dopamine D2 receptor gene (DRD2) and tri-dimensional personality questionnaire (TPQ) scores could be used to aid adjustment of daily methadone requirements of heroin addic...

    Min-Wei Huang, Tai-An Chiang, Pei-Yu Lo and Ching-Shan Huang

    Behavioral and Brain Functions 2016 12:24

    Published on: 31 August 2016

  5. Research

    Associations between the neuron-specific glucocorticoid receptor (NR3C1) Bcl-1 polymorphisms and suicide in cancer patients within the first year of diagnosis

    Cancer diagnosis is associated with an increased suicide risk, particularly within the first 1 year after diagnosis of cancer. Abnormal function of the hypothalamic–pituitary–adrenal axis has been implicated i...

    Subin Park, Jin Pyo Hong, Jong-Keuk Lee, Young-Mi Park, Yangsoon Park, Juri Jeon, Myeong Hee Ahn and Se Chang Yoon

    Behavioral and Brain Functions 2016 12:22

    Published on: 11 July 2016

  6. Research

    The effect of epilepsy on autistic symptom severity assessed by the social responsiveness scale in children with autism spectrum disorder

    As the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two...

    Chanyoung Ko, Namwook Kim, Eunjoo Kim, Dong Ho Song and Keun-Ah Cheon

    Behavioral and Brain Functions 2016 12:20

    Published on: 27 June 2016

  7. Research

    Chronic cigarette smoking is linked with structural alterations in brain regions showing acute nicotinic drug-induced functional modulations

    Whereas acute nicotine administration alters brain function which may, in turn, contribute to enhanced attention and performance, chronic cigarette smoking is linked with regional brain atrophy and poorer cogn...

    Matthew T. Sutherland, Michael C. Riedel, Jessica S. Flannery, Julio A. Yanes, Peter T. Fox, Elliot A. Stein and Angela R. Laird

    Behavioral and Brain Functions 2016 12:16

    Published on: 2 June 2016

  8. Research

    Oral administration of potassium bromate induces neurobehavioral changes, alters cerebral neurotransmitters level and impairs brain tissue of swiss mice

    Potassium bromate (KBrO3) is widely used as a food additive and is a major water disinfection by-product. The present study reports the side effects of KBrO3 administration on the brain functions and behaviour of...

    Jamaan Ajarem, Naif G. Altoom, Ahmed A. Allam, Saleh N. Maodaa, Mostafa A. Abdel- Maksoud and Billy KC. Chow

    Behavioral and Brain Functions 2016 12:14

    Published on: 12 May 2016

  10. Research

    Non-targeted metabolite profiling reveals changes in oxidative stress, tryptophan and lipid metabolisms in fearful dogs

    Anxieties, such as shyness, noise phobia and separation anxiety, are common but poorly understood behavioural problems in domestic dogs, Canis familiaris. Although studies have demonstrated genetic and environmen...

    Jenni Puurunen, Katriina Tiira, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Behavioral and Brain Functions 2016 12:7

    Published on: 12 February 2016

  11. Research

    Effect of parsley (Petroselinum crispum, Apiaceae) juice against cadmium neurotoxicity in albino mice (Mus Musculus)

    Parsley was employed as an experimental probe to prevent the behavioral, biochemical and morphological changes in the brain tissue of the albino mice following chronic cadmium (Cd) administration.

    Saleh N. Maodaa, Ahmed A. Allam, Jamaan Ajarem, Mostafa A. Abdel-Maksoud, Gadah I. Al-Basher and Zun Yao Wang

    Behavioral and Brain Functions 2016 12:6

    Published on: 4 February 2016

  14. Research

    4′-O-β-d-glucosyl-5-O-methylvisamminol, an active ingredient of Saposhnikovia divaricata, attenuates high-mobility group box 1 and subarachnoid hemorrhage-induced vasospasm in a rat model

    High-mobility group box 1 (HMGB1) was observed to be an important extracellular mediator involved in vascular inflammation associated with subarachnoid hemorrhage (SAH). This study is of interest to examine th...

    Chih-Zen Chang, Shu-Chuan Wu, Aij-Lie Kwan and Chih-Lung Lin

    Behavioral and Brain Functions 2015 11:28

    Published on: 22 September 2015

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