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Neurobiology of brain disorders

  1. Schizophrenia research arose in the twentieth century and is currently rapidly developing, focusing on many parallel research pathways and evaluating various concepts of disease etiology. Today, we have relati...

    Authors: Enrico Patrono, Jan Svoboda and Aleš Stuchlík

    Citation: Behavioral and Brain Functions 2021 17:7

    Content type: Review

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  2. Aging is the leading risk factor for several age-associated diseases such as neurodegenerative diseases. Understanding the biology of aging mechanisms is essential to the pursuit of brain health. In this regar...

    Authors: Aliabbas Zia, Ali Mohammad Pourbagher-Shahri, Tahereh Farkhondeh and Saeed Samarghandian

    Citation: Behavioral and Brain Functions 2021 17:6

    Content type: Review

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  3. Obsessive–compulsive disorder (OCD) is a mental disease with heterogeneous behavioral phenotypes, including repetitive behaviors, anxiety, and impairments in cognitive functions. The brain regions related to t...

    Authors: Xiao Chen, Jihui Yue, Yuchong Luo, Lianyan Huang, Boxing Li and Shenglin Wen

    Citation: Behavioral and Brain Functions 2021 17:4

    Content type: Research

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  4. Middle-aged females, especially perimenopausal females, are vulnerable to depression, but the potential mechanism remains unclear. Dopaminergic and GABAergic system dysfunction is involved in the pathophysiolo...

    Authors: Guofen Cao, Gaili Meng, Li Zhu, Jie Zhu, Nan Dong, Xiaolan Zhou, Sumei Zhang and Yongai Zhang

    Citation: Behavioral and Brain Functions 2021 17:2

    Content type: Research

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  5. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons leading to dopamine depletion and problems of movement, emotions, and cog...

    Authors: Dina M. Monir, Motamed E. Mahmoud, Omyma G. Ahmed, Ibrahim F. Rehan and Amany Abdelrahman

    Citation: Behavioral and Brain Functions 2020 16:9

    Content type: Research

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  6. Maternal immune activation (MIA) during gestation can increase the later risk of schizophrenia in adult offspring. Neuroinflammation is believed to underlie this process. Postmortem brain studies have found ch...

    Authors: Shuang Ding, Yunqing Hu, Binbin Luo, Yaqi Cai, Keke Hao, Yongfeng Yang, Yan Zhang, Xiujuan Wang, Minli Ding, Hongxing Zhang, Wenqiang Li and Luxian Lv

    Citation: Behavioral and Brain Functions 2019 15:3

    Content type: Research

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  7. Signs of pervasive developmental disorder and social deficits were reported in toddlers and children whose mothers were exposed to organophosphate pesticides during pregnancy. Deficits in social preference wer...

    Authors: Anat Lan, Daniel Stein, Miguel Portillo, Debra Toiber and Ora Kofman

    Citation: Behavioral and Brain Functions 2019 15:2

    Content type: Research

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  9. Narcolepsy is a chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. This disease affects significantly the overall patient functioni...

    Authors: C. Schiappa, S. Scarpelli, A. D’Atri, M. Gorgoni and Luigi De Gennaro

    Citation: Behavioral and Brain Functions 2018 14:19

    Content type: Review

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  10. Schizophrenia (SZ) is a complex polygenic psychiatric disorder caused in part by abnormal dopamine levels. Cerebral dopamine neurotrophic factor (CDNF) 2 is known to protect and repair the dopaminergic system. Do...

    Authors: Yongfeng Yang, Hongyan Yu, Wenqiang Li, Bing Liu, Hongxing Zhang, Shuang Ding, Yanli Lu, Tianzi Jiang and Luxian Lv

    Citation: Behavioral and Brain Functions 2018 14:1

    Content type: Research

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  11. Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs. We investigated whether the drug MPTP produces the olfactor...

    Authors: Carla Mucignat and Antonio Caretta

    Citation: Behavioral and Brain Functions 2017 13:1

    Content type: Short paper

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  12. Attention deficit hyperactivity disorder (ADHD) is a prevalent and multifactorial neuropsychiatric disorder in the human population worldwide. Complex etiology and clinical heterogeneity have challenged the re...

    Authors: Jenni Puurunen, Sini Sulkama, Katriina Tiira, Cesar Araujo, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Citation: Behavioral and Brain Functions 2016 12:27

    Content type: Research

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  13. To reduce the number of patients with depression, biomarkers for clarifying psychiatric disorders are warranted. Numerous candidates have been proposed; however, near-infrared spectroscopy (NIRS) with multi-ch...

    Authors: Shinya Kinoshita, Tetsufumi Kanazawa, Hiroki Kikuyama and Hiroshi Yoneda

    Citation: Behavioral and Brain Functions 2016 12:25

    Content type: Research

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  14. We investigated whether variation in the dopamine D2 receptor gene (DRD2) and tri-dimensional personality questionnaire (TPQ) scores could be used to aid adjustment of daily methadone requirements of heroin addic...

    Authors: Min-Wei Huang, Tai-An Chiang, Pei-Yu Lo and Ching-Shan Huang

    Citation: Behavioral and Brain Functions 2016 12:24

    Content type: Research

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  15. Cancer diagnosis is associated with an increased suicide risk, particularly within the first 1 year after diagnosis of cancer. Abnormal function of the hypothalamic–pituitary–adrenal axis has been implicated i...

    Authors: Subin Park, Jin Pyo Hong, Jong-Keuk Lee, Young-Mi Park, Yangsoon Park, Juri Jeon, Myeong Hee Ahn and Se Chang Yoon

    Citation: Behavioral and Brain Functions 2016 12:22

    Content type: Research

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  16. As the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two...

    Authors: Chanyoung Ko, Namwook Kim, Eunjoo Kim, Dong Ho Song and Keun-Ah Cheon

    Citation: Behavioral and Brain Functions 2016 12:20

    Content type: Research

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  17. Whereas acute nicotine administration alters brain function which may, in turn, contribute to enhanced attention and performance, chronic cigarette smoking is linked with regional brain atrophy and poorer cogn...

    Authors: Matthew T. Sutherland, Michael C. Riedel, Jessica S. Flannery, Julio A. Yanes, Peter T. Fox, Elliot A. Stein and Angela R. Laird

    Citation: Behavioral and Brain Functions 2016 12:16

    Content type: Research

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  18. Potassium bromate (KBrO3) is widely used as a food additive and is a major water disinfection by-product. The present study reports the side effects of KBrO3 administration on the brain functions and behaviour of...

    Authors: Jamaan Ajarem, Naif G. Altoom, Ahmed A. Allam, Saleh N. Maodaa, Mostafa A. Abdel- Maksoud and Billy KC. Chow

    Citation: Behavioral and Brain Functions 2016 12:14

    Content type: Research

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  20. Anxieties, such as shyness, noise phobia and separation anxiety, are common but poorly understood behavioural problems in domestic dogs, Canis familiaris. Although studies have demonstrated genetic and environmen...

    Authors: Jenni Puurunen, Katriina Tiira, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Citation: Behavioral and Brain Functions 2016 12:7

    Content type: Research

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  21. Parsley was employed as an experimental probe to prevent the behavioral, biochemical and morphological changes in the brain tissue of the albino mice following chronic cadmium (Cd) administration.

    Authors: Saleh N. Maodaa, Ahmed A. Allam, Jamaan Ajarem, Mostafa A. Abdel-Maksoud, Gadah I. Al-Basher and Zun Yao Wang

    Citation: Behavioral and Brain Functions 2016 12:6

    Content type: Research

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  22. Autism spectrum disorder (ASD) refers to a broad spectrum of neurodevelopmental disorders characterized by three central behavioral symptoms: impaired social interaction, impaired social communication, and res...

    Authors: Hyopil Kim, Chae-Seok Lim and Bong-Kiun Kaang

    Citation: Behavioral and Brain Functions 2016 12:3

    Content type: Review

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  23. To investigate the effects of microglia/macrophages activation induced by intrastriatal thrombin injection on dentate gyrus neurogenesis and spatial memory ability in mice.

    Authors: Yuan Yang, Meikui Zhang, Xiaoni Kang, Chen Jiang, Huan Zhang, Pei Wang and Jingjing Li

    Citation: Behavioral and Brain Functions 2015 11:30

    Content type: Research

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  24. High-mobility group box 1 (HMGB1) was observed to be an important extracellular mediator involved in vascular inflammation associated with subarachnoid hemorrhage (SAH). This study is of interest to examine th...

    Authors: Chih-Zen Chang, Shu-Chuan Wu, Aij-Lie Kwan and Chih-Lung Lin

    Citation: Behavioral and Brain Functions 2015 11:28

    Content type: Research

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Behavioral and Brain Functions

ISSN: 1744-9081

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