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Neurobiology of brain disorders

  1. Content type: Research

    Schizophrenia (SZ) is a complex polygenic psychiatric disorder caused in part by abnormal dopamine levels. Cerebral dopamine neurotrophic factor (CDNF) 2 is known to protect and repair the dopaminergic system. Do...

    Authors: Yongfeng Yang, Hongyan Yu, Wenqiang Li, Bing Liu, Hongxing Zhang, Shuang Ding, Yanli Lu, Tianzi Jiang and Luxian Lv

    Citation: Behavioral and Brain Functions 2018 14:1

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  2. Content type: Short paper

    Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs. We investigated whether the drug MPTP produces the olfactor...

    Authors: Carla Mucignat and Antonio Caretta

    Citation: Behavioral and Brain Functions 2017 13:1

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  3. Content type: Research

    Attention deficit hyperactivity disorder (ADHD) is a prevalent and multifactorial neuropsychiatric disorder in the human population worldwide. Complex etiology and clinical heterogeneity have challenged the re...

    Authors: Jenni Puurunen, Sini Sulkama, Katriina Tiira, Cesar Araujo, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Citation: Behavioral and Brain Functions 2016 12:27

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  4. Content type: Research

    To reduce the number of patients with depression, biomarkers for clarifying psychiatric disorders are warranted. Numerous candidates have been proposed; however, near-infrared spectroscopy (NIRS) with multi-ch...

    Authors: Shinya Kinoshita, Tetsufumi Kanazawa, Hiroki Kikuyama and Hiroshi Yoneda

    Citation: Behavioral and Brain Functions 2016 12:25

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  5. Content type: Research

    We investigated whether variation in the dopamine D2 receptor gene (DRD2) and tri-dimensional personality questionnaire (TPQ) scores could be used to aid adjustment of daily methadone requirements of heroin addic...

    Authors: Min-Wei Huang, Tai-An Chiang, Pei-Yu Lo and Ching-Shan Huang

    Citation: Behavioral and Brain Functions 2016 12:24

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  6. Content type: Research

    Cancer diagnosis is associated with an increased suicide risk, particularly within the first 1 year after diagnosis of cancer. Abnormal function of the hypothalamic–pituitary–adrenal axis has been implicated i...

    Authors: Subin Park, Jin Pyo Hong, Jong-Keuk Lee, Young-Mi Park, Yangsoon Park, Juri Jeon, Myeong Hee Ahn and Se Chang Yoon

    Citation: Behavioral and Brain Functions 2016 12:22

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  7. Content type: Research

    As the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two...

    Authors: Chanyoung Ko, Namwook Kim, Eunjoo Kim, Dong Ho Song and Keun-Ah Cheon

    Citation: Behavioral and Brain Functions 2016 12:20

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  8. Content type: Research

    Whereas acute nicotine administration alters brain function which may, in turn, contribute to enhanced attention and performance, chronic cigarette smoking is linked with regional brain atrophy and poorer cogn...

    Authors: Matthew T. Sutherland, Michael C. Riedel, Jessica S. Flannery, Julio A. Yanes, Peter T. Fox, Elliot A. Stein and Angela R. Laird

    Citation: Behavioral and Brain Functions 2016 12:16

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  9. Content type: Research

    Potassium bromate (KBrO3) is widely used as a food additive and is a major water disinfection by-product. The present study reports the side effects of KBrO3 administration on the brain functions and behaviour of...

    Authors: Jamaan Ajarem, Naif G. Altoom, Ahmed A. Allam, Saleh N. Maodaa, Mostafa A. Abdel- Maksoud and Billy KC. Chow

    Citation: Behavioral and Brain Functions 2016 12:14

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  10. Content type: Research

    Anxieties, such as shyness, noise phobia and separation anxiety, are common but poorly understood behavioural problems in domestic dogs, Canis familiaris. Although studies have demonstrated genetic and environmen...

    Authors: Jenni Puurunen, Katriina Tiira, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Citation: Behavioral and Brain Functions 2016 12:7

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  11. Content type: Research

    Parsley was employed as an experimental probe to prevent the behavioral, biochemical and morphological changes in the brain tissue of the albino mice following chronic cadmium (Cd) administration.

    Authors: Saleh N. Maodaa, Ahmed A. Allam, Jamaan Ajarem, Mostafa A. Abdel-Maksoud, Gadah I. Al-Basher and Zun Yao Wang

    Citation: Behavioral and Brain Functions 2016 12:6

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  12. Content type: Review

    Autism spectrum disorder (ASD) refers to a broad spectrum of neurodevelopmental disorders characterized by three central behavioral symptoms: impaired social interaction, impaired social communication, and res...

    Authors: Hyopil Kim, Chae-Seok Lim and Bong-Kiun Kaang

    Citation: Behavioral and Brain Functions 2016 12:3

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  13. Content type: Research

    To investigate the effects of microglia/macrophages activation induced by intrastriatal thrombin injection on dentate gyrus neurogenesis and spatial memory ability in mice.

    Authors: Yuan Yang, Meikui Zhang, Xiaoni Kang, Chen Jiang, Huan Zhang, Pei Wang and Jingjing Li

    Citation: Behavioral and Brain Functions 2015 11:30

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  14. Content type: Research

    High-mobility group box 1 (HMGB1) was observed to be an important extracellular mediator involved in vascular inflammation associated with subarachnoid hemorrhage (SAH). This study is of interest to examine th...

    Authors: Chih-Zen Chang, Shu-Chuan Wu, Aij-Lie Kwan and Chih-Lung Lin

    Citation: Behavioral and Brain Functions 2015 11:28

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